The in Vitro Combined Effect of Sulfisoxazole with Antituberculous Agents. Report Ii
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چکیده
The authors') studied previously on the in vitro combined effect of sulfisoxazole with antituberculous agents and reported that the effect consisted of the heterogeneous composition of bacterial population with regard to drug sensitivity and the retarding action of drugs on the generation time of the organism. This study concerned with the effect of sulfisoxazole with antituberculous agents inhibitory for a few individual cells of bacterial population. The present paper concerns with the combined effect of sulfisoxazole with antituberculous agents inhibitory for a greater part of individual cells of bacterial' population and not inhibitory for resistant mutants and it concerns also with the mechanism of effect of sulfisoxazole in retarding the resistance to antituberculous agents.
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تاریخ انتشار 2010